1761, 9th edition
John Wesley published the first edition of his 'Primitive Physick' in 1747. Wesley had a life-long interest in health, in that only physical and spiritual health in combination could make for healthy people. This was unusual at that time.
The book was both an overall preventive approach to health and a compendium of remedies for specific ailments - in total more than 800 prescriptions for more than 300 different disorders. It was very popular throughout the 18th century and by the time Wesley died in 1791, the book had gone through twenty-three editions.